For the 1972 model year, the Limited Edition Regency was offered to commemorate Oldsmobile's 75th anniversary. Each 1972 Oldsmobile Ninety-Eight Regency was registered at Tiffany's and included the specially styled interior with a black or covert "pillow effect" velour upholstery, and power split bench seat, in place of the power bench seat with rear clock. Tiffany touches include the Tiffany Gold paint (an exclusive custom metallic color created especially for this car), the clock has also been specially styled by Tiffany's and bears a white Oldsmobile emblem above the Tiffany's name on a golden face. Each 1972 Regency owner received a distinctive sterling silver key ring as a gift, if ever lost the keys could be dropped in a mail box, and Tiffany's would return them to the owner. A total of 2650 75th anniversary Ninety-Eight Regencys were built, all of them four-door hardtops. In 1973 the non-anniversary Regency stayed in the line up slotted just above the LS. The Regency package would remain available on the Ninety Eight throughout the 1996 model year when it would become a separate model nameplate.
The Ninety-Eight was restyled for 1980, along with the Delta 88. 1981 saw the introduction of Buick's 252 in³ V6 as standard, as well as a new 4-speed THM200-4R automatic transmission. The new Regency Brougham model was introduced for 1982. This car featured plush "Prima" velour seats with embroidered emblems, cut pile carpeting, and electroluminescent opera lamps on the B-pillars.